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POSH Regulates CD4(+) T cell Differentiation and Survival

The scaffold molecule POSH is crucial for the regulation of proliferation and effector function in CD8(+) T cells. However, its role in CD4(+) T cells is not known. Here we found that, disruption of the POSH scaffold complex established a transcriptional profile that strongly skewed differentiation...

詳細記述

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書誌詳細
出版年:J Immunol
主要な著者: Cunningham, Cody A., Cardwell, Leah N., Guan, Yue, Teixeiro, Emma, Daniels, Mark A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868786/
https://ncbi.nlm.nih.gov/pubmed/27084103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501728
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