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CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40

Secondary T cell responses are enhanced because of an expansion in numbers of antigen-specific (memory) cells. Using major histocompatibility complex class II tetramers we have tracked peptide-specific endogenous (non–T cell receptor transgenic) CD4 memory T cells in normal and in costimulation-defi...

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Autores principales: MacLeod, Megan, Kwakkenbos, Mark J., Crawford, Alison, Brown, Sheila, Stockinger, Brigitta, Schepers, Koen, Schumacher, Ton, Gray, David
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118277/
https://ncbi.nlm.nih.gov/pubmed/16549596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050711
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