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POSH Regulates CD4(+) T cell Differentiation and Survival
The scaffold molecule POSH is crucial for the regulation of proliferation and effector function in CD8(+) T cells. However, its role in CD4(+) T cells is not known. Here we found that, disruption of the POSH scaffold complex established a transcriptional profile that strongly skewed differentiation...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868786/ https://ncbi.nlm.nih.gov/pubmed/27084103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501728 |
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