Fast clearance of lipid droplets through MAP1S-activated autophagy suppresses clear cell renal cell carcinomas and promotes patient survival

Clear cell renal cell carcinoma (ccRCC) is composed of cells whose cytoplasm filled with lipid droplets, subcellular organelles coated with adipocyte differentiation-related protein (ADFP) for the storage of triacylglycerol converted from excess free fatty acids. Mammalian cells primarily use the au...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Guibin, Jiang, Yaodong, Xiao, Yuansong, Liu, Xian-De, Yue, Fei, Li, Wenjiao, Li, Xun, He, Yongzhong, Jiang, Xianhan, Huang, Hai, Chen, Qi, Jonasch, Eric, Liu, Leyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868754/
https://ncbi.nlm.nih.gov/pubmed/26701856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6669
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