N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins

Pseudomonas aeruginosa produces N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule for bacterial communication. C12 has also been reported to induce apoptosis in various types of tumor cells. However, the detailed molecular mechanism of C12-triggerred tumor cell apoptosis is s...

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Pubblicato in:Oncotarget
Autori principali: Zhao, Guoping, Neely, Aaron M., Schwarzer, Christian, Lu, Huayi, Whitt, Aaron G., Stivers, Nicole S., Burlison, Joseph A., White, Carl, Machen, Terry E., Li, Chi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868731/
https://ncbi.nlm.nih.gov/pubmed/26758417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6827
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