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Induction of autophagy promotes the growth of early preneoplastic rat liver nodules

Although inhibition of autophagy has been implicated in the onset and progression of cancer cells, it is still unclear whether its dysregulation at early stages of tumorigenesis plays an oncogenic or a tumor suppressor role. To address this question, we employed the Resistant-Hepatocyte rat model to...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Kowalik, Marta Anna, Perra, Andrea, Ledda-Columbano, Giovanna Maria, Ippolito, Giuseppe, Piacentini, Mauro, Columbano, Amedeo, Falasca, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868721/
https://ncbi.nlm.nih.gov/pubmed/26735341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6810
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