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Induction of autophagy promotes the growth of early preneoplastic rat liver nodules

Although inhibition of autophagy has been implicated in the onset and progression of cancer cells, it is still unclear whether its dysregulation at early stages of tumorigenesis plays an oncogenic or a tumor suppressor role. To address this question, we employed the Resistant-Hepatocyte rat model to...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kowalik, Marta Anna, Perra, Andrea, Ledda-Columbano, Giovanna Maria, Ippolito, Giuseppe, Piacentini, Mauro, Columbano, Amedeo, Falasca, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868721/
https://ncbi.nlm.nih.gov/pubmed/26735341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6810
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