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Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis

Although the expression of the stem/progenitor cell marker cytokeratin-19 (CK-19) has been associated with the worst clinical prognosis among all HCC subclasses, it is yet unknown whether its presence in HCC is the result of clonal expansion of hepatic progenitor cells (HPCs) or of de-differentiatio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kowalik, Marta Anna, Sulas, Pia, Ledda-Columbano, Giovanna Maria, Giordano, Silvia, Columbano, Amedeo, Perra, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770734/
https://ncbi.nlm.nih.gov/pubmed/26452031
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