Enhanced glucose transport, but not phosphorylation capacity, ameliorates lipopolysaccharide-induced impairments in insulin stimulated-muscle glucose uptake

Lipopolysaccharide (LPS) is known to impair insulin stimulated muscle glucose uptake. We determined if increased glucose transport (GLUT4) or phosphorylation capacity (hexokinase II; HKII) could overcome the impairment in muscle glucose uptake (MGU). We utilized mice that over-expressed GLUT4 (GLUT4...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Shock
Hauptverfasser: Otero, Yolanda F., Mulligan, Kimberly X., Barnes, Tammy M., Ford, Eric A., Malabanan, Carlo M., Zong, Haihong, Pessin, Jeffrey E., Wasserman, David H., Guinness, Owen P.M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868638/
https://ncbi.nlm.nih.gov/pubmed/26682946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000550
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge