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A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

Small G-proteins of the ADP-ribosylation-factor-like (Arl) subfamily have been shown to be crucial to ciliogenesis and cilia maintenance. Active Arl3 is involved in targeting and releasing lipidated cargo proteins from their carriers PDE6δ and UNC119a/b to the cilium. However, the guanine nucleotide...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:eLife
Egile Nagusiak: Gotthardt, Katja, Lokaj, Mandy, Koerner, Carolin, Falk, Nathalie, Gießl, Andreas, Wittinghofer, Alfred
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868535/
https://ncbi.nlm.nih.gov/pubmed/26551564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11859
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