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A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

Small G-proteins of the ADP-ribosylation-factor-like (Arl) subfamily have been shown to be crucial to ciliogenesis and cilia maintenance. Active Arl3 is involved in targeting and releasing lipidated cargo proteins from their carriers PDE6δ and UNC119a/b to the cilium. However, the guanine nucleotide...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Gotthardt, Katja, Lokaj, Mandy, Koerner, Carolin, Falk, Nathalie, Gießl, Andreas, Wittinghofer, Alfred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868535/
https://ncbi.nlm.nih.gov/pubmed/26551564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11859
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