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Evidence for pericyte origin of TSC-associated renal angiomyolipomas and implications for angiotensin receptor inhibition therapy

Nearly all patients with tuberous sclerosis complex (TSC) develop renal angiomyolipomas, although the tumor cell of origin is unknown. We observed decreased renal angiomyolipoma development in patients with TSC2- polycystic kidney disease 1 deletion syndrome and hypertension that were treated from a...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Siroky, Brian J., Yin, Hong, Dixon, Bradley P., Reichert, Ryan J., Hellmann, Anna R., Ramkumar, Thiruvamoor, Tsuchihashi, Zenta, Bunni, Marlene, Dillon, Joshua, Bell, P. Darwin, Sampson, Julian R., Bissler, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868369/
https://ncbi.nlm.nih.gov/pubmed/24920756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00569.2013
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