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Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress
Tuberous sclerosis complex (TSC), an inherited tumor predisposition syndrome associated with mutations in TSC1 or TSC2, affects ∼1 in 6,000 individuals. Eighty percent of TSC patients develop renal angiomyolipomas, and renal involvement is a major contributor to patient morbidity and mortality. Rece...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468523/ https://ncbi.nlm.nih.gov/pubmed/22791333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00441.2011 |
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