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Fibulin-1 suppresses endothelial to mesenchymal transition in the proximal outflow tract

Endothelial to mesenchymal transition (EMT) that occurs during cardiac outflow tract (OFT) development is critical for formation of the semilunar valves. Fibulin-1 (Fbln1) is an extra-cellular matrix protein that is present at several sites of EMT, including the OFT (i.e., E9.5–10.5). The aim of thi...

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Библиографические подробности
Опубликовано в: :Mech Dev
Главные авторы: Harikrishnan, Keerthi, Cooley, Marion A., Sugi, Yukiko, Barth, Jeremy L., Rasmussen, Lars M., Kern, Christine B., Argraves, Kelley M., Argraves, W. Scott
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868094/
https://ncbi.nlm.nih.gov/pubmed/25575930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2014.12.005
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