טוען...
Ozanimod (RPC1063) is a potent sphingosine‐1‐phosphate receptor‐1 (S1P(1)) and receptor‐5 (S1P(5)) agonist with autoimmune disease‐modifying activity
BACKGROUND AND PURPOSE: Sphingosine1‐phosphate (S1P) receptors mediate multiple events including lymphocyte trafficking, cardiac function, and endothelial barrier integrity. Stimulation of S1P(1) receptors sequesters lymphocyte subsets in peripheral lymphoid organs, preventing their trafficking to i...
שמור ב:
הוצא לאור ב: | Br J Pharmacol |
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Main Authors: | , , , , , , , , , , , , |
פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
John Wiley and Sons Inc.
2016
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867749/ https://ncbi.nlm.nih.gov/pubmed/26990079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13476 |
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