New use for an old drug: COX‐independent anti‐inflammatory effects of sulindac in models of cystic fibrosis

BACKGROUND AND PURPOSE: Pulmonary disease is the main cause of morbidity and mortality in cystic fibrosis (CF) patients due to exacerbated inflammation. To date, the only anti‐inflammatory drug available to CF patients is high‐dose ibuprofen, which can slow pulmonary disease progression, but whose c...

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Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Rocca, Jérémy, Manin, Sylvie, Hulin, Anne, Aissat, Abdel, Verbecq‐Morlot, Wilfried, Prulière‐Escabasse, Virginie, Wohlhuter‐Haddad, Adeline, Epaud, Ralph, Fanen, Pascale, Tarze, Agathe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2016
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867744/
https://ncbi.nlm.nih.gov/pubmed/26894321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13464
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