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5‐HT(3) receptors promote colonic inflammation via activation of substance P/neurokinin‐1 receptors in dextran sulphate sodium‐induced murine colitis

BACKGROUND AND PURPOSE: 5‐HT (serotonin) regulates various physiological functions, both directly and via enteric neurons. The present study investigated the role of endogenous 5‐HT and 5‐HT(3) receptors in the pathogenic mechanisms involved in colonic inflammation, especially in relation to substan...

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Foilsithe in:Br J Pharmacol
Main Authors: Utsumi, Daichi, Matsumoto, Kenjiro, Amagase, Kikuko, Horie, Syunji, Kato, Shinichi
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867739/
https://ncbi.nlm.nih.gov/pubmed/26990520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13482
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