5‐HT(3) receptors promote colonic inflammation via activation of substance P/neurokinin‐1 receptors in dextran sulphate sodium‐induced murine colitis

BACKGROUND AND PURPOSE: 5‐HT (serotonin) regulates various physiological functions, both directly and via enteric neurons. The present study investigated the role of endogenous 5‐HT and 5‐HT(3) receptors in the pathogenic mechanisms involved in colonic inflammation, especially in relation to substan...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Utsumi, Daichi, Matsumoto, Kenjiro, Amagase, Kikuko, Horie, Syunji, Kato, Shinichi
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867739/
https://ncbi.nlm.nih.gov/pubmed/26990520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13482
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