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5‐HT(3) receptors promote colonic inflammation via activation of substance P/neurokinin‐1 receptors in dextran sulphate sodium‐induced murine colitis
BACKGROUND AND PURPOSE: 5‐HT (serotonin) regulates various physiological functions, both directly and via enteric neurons. The present study investigated the role of endogenous 5‐HT and 5‐HT(3) receptors in the pathogenic mechanisms involved in colonic inflammation, especially in relation to substan...
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| Publicado en: | Br J Pharmacol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867739/ https://ncbi.nlm.nih.gov/pubmed/26990520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13482 |
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