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Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction

[Image: see text] GPR4, a pH-sensing G protein-coupled receptor, is highly expressed in endothelial cells and may be activated in myocardial infarction due the decreased tissue pH. We are interested in GPR4 antagonists as potential effective pharmacologic tools and/or drug leads for the treatment of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:ACS Med Chem Lett
मुख्य लेखकों: Fukuda, Hayato, Ito, Saki, Watari, Kenji, Mogi, Chihiro, Arisawa, Mitsuhiro, Okajima, Fumikazu, Kurose, Hitoshi, Shuto, Satoshi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2016
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867472/
https://ncbi.nlm.nih.gov/pubmed/27190599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00014
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