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Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction
[Image: see text] GPR4, a pH-sensing G protein-coupled receptor, is highly expressed in endothelial cells and may be activated in myocardial infarction due the decreased tissue pH. We are interested in GPR4 antagonists as potential effective pharmacologic tools and/or drug leads for the treatment of...
में बचाया:
| में प्रकाशित: | ACS Med Chem Lett |
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| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Chemical
Society
2016
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| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867472/ https://ncbi.nlm.nih.gov/pubmed/27190599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00014 |
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