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Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction
[Image: see text] GPR4, a pH-sensing G protein-coupled receptor, is highly expressed in endothelial cells and may be activated in myocardial infarction due the decreased tissue pH. We are interested in GPR4 antagonists as potential effective pharmacologic tools and/or drug leads for the treatment of...
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| Yayımlandı: | ACS Med Chem Lett |
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| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2016
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4867472/ https://ncbi.nlm.nih.gov/pubmed/27190599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00014 |
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