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Modulation of Ca(2+) oscillation and melatonin secretion by BK(Ca) channel activity in rat pinealocytes

The pineal glands regulate circadian rhythm through the synthesis and secretion of melatonin. The stimulation of nicotinic acetylcholine receptor due to parasympathetic nerve activity causes an increase in intracellular Ca(2+) concentration and eventually downregulates melatonin production. Our prev...

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Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Mizutani, Hiroya, Yamamura, Hisao, Muramatsu, Makoto, Hagihara, Yumiko, Suzuki, Yoshiaki, Imaizumi, Yuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867307/
https://ncbi.nlm.nih.gov/pubmed/26791489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00342.2015
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