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TMEM16A and TMEM16B channel proteins generate Ca(2+)-activated Cl(−) current and regulate melatonin secretion in rat pineal glands

Pinealocytes regulate circadian rhythm by synthesizing and secreting melatonin. These cells generate action potentials; however, the contribution of specific ion channels to melatonin secretion from pinealocytes remains unclear. In this study, the involvement and molecular identity of Ca(2+)-activat...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yamamura, Hisao, Nishimura, Kaori, Hagihara, Yumiko, Suzuki, Yoshiaki, Imaizumi, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777270/
https://ncbi.nlm.nih.gov/pubmed/29187602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000326
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