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A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BK(Ca) channels in the Ca(2+) microdomain of vascular smooth muscle

Functional coupling between large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in the plasma membrane (PM) and ryanodine receptors (RyRs) in the sarcoplasmic reticulum (SR) is an essential mechanism for regulating mechanical force in most smooth muscle (SM) tissues. Spontaneous Ca(2+) release...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Saeki, Takanori, Suzuki, Yoshiaki, Yamamura, Hisao, Takeshima, Hiroshi, Imaizumi, Yuji
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721949/
https://ncbi.nlm.nih.gov/pubmed/31308177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008342
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