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A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BK(Ca) channels in the Ca(2+) microdomain of vascular smooth muscle

Functional coupling between large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in the plasma membrane (PM) and ryanodine receptors (RyRs) in the sarcoplasmic reticulum (SR) is an essential mechanism for regulating mechanical force in most smooth muscle (SM) tissues. Spontaneous Ca(2+) release...

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Vydáno v:J Biol Chem
Hlavní autoři: Saeki, Takanori, Suzuki, Yoshiaki, Yamamura, Hisao, Takeshima, Hiroshi, Imaizumi, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721949/
https://ncbi.nlm.nih.gov/pubmed/31308177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008342
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