Chemotherapy-induced Inflammatory Gene Signature and Pro-tumorigenic Phenotype in Pancreatic CAFs via Stress-associated MAPK

Pancreatic ductal adenocarcinoma (PDAC) has a characteristically dense stroma comprised predominantly of cancer associated fibroblasts (CAFs). CAFs promote tumor growth, metastasis and treatment resistance. This study aimed to investigate the molecular changes and functional consequences associated...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Cancer Res
मुख्य लेखकों: Toste, Paul A., Nguyen, Andrew H., Kadera, Brian E., Duong, Mindy, Wu, Nanping, Gawlas, Irmina, Tran, Linh M., Bikhchandani, Mihir, Li, Luyi, Patel, Sanjeet G., Dawson, David W., Donahue, Timothy R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867256/
https://ncbi.nlm.nih.gov/pubmed/26979711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-15-0348
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