MicroRNA-21 in Pancreatic Ductal Adenocarcinoma Tumor-Associated Fibroblasts Promotes Metastasis

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is projected to rise to the second leading cause of U.S. cancer-related deaths by 2020. Novel therapeutic targets are desperately needed. MicroRNAs (miRs) are small noncoding RNAs that function by suppressing gene expression and are dysregulated...

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Autors principals: Kadera, Brian E., Li, Luyi, Toste, Paul A., Wu, Nanping, Adams, Curtis, Dawson, David W., Donahue, Timothy R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750050/
https://ncbi.nlm.nih.gov/pubmed/23991015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071978
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