The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing".

The amiloride-sensitive Na+/H+ exchanger (NHE1 human isoform) is activated in response to diverse mitogenic and oncogenic signals presumably through phosphorylation. To get insight into the activating mechanism, a set of deletion mutants within the C-terminal cytoplasmic domain of NHE1 has been gene...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Wakabayashi, S, Fafournoux, P, Sardet, C, Pouysségur, J
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1992
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48670/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1372444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2424
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