The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing".

The amiloride-sensitive Na+/H+ exchanger (NHE1 human isoform) is activated in response to diverse mitogenic and oncogenic signals presumably through phosphorylation. To get insight into the activating mechanism, a set of deletion mutants within the C-terminal cytoplasmic domain of NHE1 has been gene...

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Bibliografiske detaljer
Main Authors: Wakabayashi, S, Fafournoux, P, Sardet, C, Pouysségur, J
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC48670/
https://ncbi.nlm.nih.gov/pubmed/1372444
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