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Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models

Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...

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Foilsithe in:PLoS Comput Biol
Main Authors: Jacquin, Hugo, Gilson, Amy, Shakhnovich, Eugene, Cocco, Simona, Monasson, Rémi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866778/
https://ncbi.nlm.nih.gov/pubmed/27177270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004889
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