Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models

Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Comput Biol
Prif Awduron: Jacquin, Hugo, Gilson, Amy, Shakhnovich, Eugene, Cocco, Simona, Monasson, Rémi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866778/
https://ncbi.nlm.nih.gov/pubmed/27177270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004889
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