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Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models

Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Jacquin, Hugo, Gilson, Amy, Shakhnovich, Eugene, Cocco, Simona, Monasson, Rémi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866778/
https://ncbi.nlm.nih.gov/pubmed/27177270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004889
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