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Benchmarking Inverse Statistical Approaches for Protein Structure and Design with Exactly Solvable Models

Inverse statistical approaches to determine protein structure and function from Multiple Sequence Alignments (MSA) are emerging as powerful tools in computational biology. However the underlying assumptions of the relationship between the inferred effective Potts Hamiltonian and real protein structu...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Jacquin, Hugo, Gilson, Amy, Shakhnovich, Eugene, Cocco, Simona, Monasson, Rémi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866778/
https://ncbi.nlm.nih.gov/pubmed/27177270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004889
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