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High Persister Mutants in Mycobacterium tuberculosis

Mycobacterium tuberculosis forms drug-tolerant persister cells that are the probable cause of its recalcitrance to antibiotic therapy. While genetically identical to the rest of the population, persisters are dormant, which protects them from killing by bactericidal antibiotics. The mechanism of per...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Torrey, Heather L., Keren, Iris, Via, Laura E., Lee, Jong Seok, Lewis, Kim
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866775/
https://ncbi.nlm.nih.gov/pubmed/27176494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155127
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