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High Persister Mutants in Mycobacterium tuberculosis

Mycobacterium tuberculosis forms drug-tolerant persister cells that are the probable cause of its recalcitrance to antibiotic therapy. While genetically identical to the rest of the population, persisters are dormant, which protects them from killing by bactericidal antibiotics. The mechanism of per...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Torrey, Heather L., Keren, Iris, Via, Laura E., Lee, Jong Seok, Lewis, Kim
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866775/
https://ncbi.nlm.nih.gov/pubmed/27176494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155127
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