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A Method for Checking Genomic Integrity in Cultured Cell Lines from SNP Genotyping Data

Genomic screening for chromosomal abnormalities is an important part of quality control when establishing and maintaining stem cell lines. We present a new method for sensitive detection of copy number alterations, aneuploidy, and contamination in cell lines using genome-wide SNP genotyping data. In...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Danecek, Petr, McCarthy, Shane A., Durbin, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866717/
https://ncbi.nlm.nih.gov/pubmed/27176002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155014
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