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A Method for Checking Genomic Integrity in Cultured Cell Lines from SNP Genotyping Data

Genomic screening for chromosomal abnormalities is an important part of quality control when establishing and maintaining stem cell lines. We present a new method for sensitive detection of copy number alterations, aneuploidy, and contamination in cell lines using genome-wide SNP genotyping data. In...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Danecek, Petr, McCarthy, Shane A., Durbin, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866717/
https://ncbi.nlm.nih.gov/pubmed/27176002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155014
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