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SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples
Reductions in the cost of sequencing have enabled whole-genome sequencing to identify sequence variants segregating in a population. An efficient approach is to sequence many samples at low coverage, then to combine data across samples to detect shared variants. Here, we present methods to discover...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3106328/ https://ncbi.nlm.nih.gov/pubmed/20980557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.113084.110 |
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