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Comparing a few SNP calling algorithms using low-coverage sequencing data

BACKGROUND: Many Single Nucleotide Polymorphism (SNP) calling programs have been developed to identify Single Nucleotide Variations (SNVs) in next-generation sequencing (NGS) data. However, low sequencing coverage presents challenges to accurate SNV identification, especially in single-sample data....

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Autors principals: Yu, Xiaoqing, Sun, Shuying
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848615/
https://ncbi.nlm.nih.gov/pubmed/24044377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-274
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