Disruption of relative reward value by reversible disconnection of orbitofrontal and rhinal cortex using DREADDs in rhesus monkeys

To study how the interaction between orbitofrontal (OFC) and rhinal (Rh) cortices influences the judgment of reward size, we reversibly disconnected these regions using the hM4Di-DREADD (Designer Receptor Exclusively Activated by Designer Drug). Repeated inactivation reduced sensitivity to differenc...

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Bibliografiske detaljer
Udgivet i:Nat Neurosci
Main Authors: Eldridge, Mark A G, Lerchner, Walter, Saunders, Richard C, Kaneko, Hiroyuki, Krausz, Kristopher W, Gonzalez, Frank J, Ji, Bin, Higuchi, Makoto, Minamimoto, Takafumi, Richmond, Barry J
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866611/
https://ncbi.nlm.nih.gov/pubmed/26656645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4192
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