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Membrane Association of the Diphtheria Toxin Translocation Domain Studied by Coarse-Grained Simulations and Experiment

Diphtheria toxin translocation (T) domain inserts in lipid bilayers upon acidification of the environment. Computational and experimental studies have suggested that low pH triggers a conformational change of the T-domain in solution preceding membrane binding. The refolded membrane-competent state...

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Vydáno v:J Membr Biol
Hlavní autoři: Flores-Canales, Jose C., Vargas-Uribe, Mauricio, Ladokhin, Alexey S., Kurnikova, Maria
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866490/
https://ncbi.nlm.nih.gov/pubmed/25650178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-015-9771-3
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