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Ubiquitin C-terminal hydrolase 1: A novel functional marker for liver myofibroblasts and a therapeutic target in chronic liver disease

BACKGROUND & AIMS: Ubiquitination is a reversible protein modification involved in the major cellular processes that define cell phenotype and behaviour. Ubiquitin modifications are removed by a large family of proteases named deubiquitinases. The role of deubiquitinases in hepatic stellate cell...

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Bibliografiska uppgifter
I publikationen:J Hepatol
Huvudupphovsmän: Wilson, Caroline L., Murphy, Lindsay B., Leslie, Jack, Kendrick, Stuart, French, Jeremy, Fox, Christopher R., Sheerin, Neil S., Fisher, Andrew, Robinson, John H., Tiniakos, Dina G., Gray, Douglas A., Oakley, Fiona, Mann, Derek A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4866442/
https://ncbi.nlm.nih.gov/pubmed/26264933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.07.034
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