Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity

BACKGROUND: Numerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk have increased toxicity following radiotherapy. M...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Ahmed, Mahbubl, Dorling, Leila, Kerns, Sarah, Fachal, Laura, Elliott, Rebecca, Partliament, Matt, Rosenstein, Barry S, Vega, Ana, Gómez-Caamaño, Antonio, Barnett, Gill, Dearnaley, David P, Hall, Emma, Sydes, Matt, Burnet, Neil, Pharoah, Paul D P, Eeles, Ros, West, Catharine M L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865979/
https://ncbi.nlm.nih.gov/pubmed/27070714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.94
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