טוען...
Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders
Germline loss- and gain-of-function mutations of G-protein α-11 (Gα(11)), which couples the calcium-sensing receptor (CaSR) to intracellular calcium (Ca(2+)(i)) signaling, lead to familial hypocalciuric hypercalcemia type 2 (FHH2) and autosomal dominant hypocalcemia type 2 (ADH2), respectively, wher...
שמור ב:
| הוצא לאור ב: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865932/ https://ncbi.nlm.nih.gov/pubmed/26994139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696401 |
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