Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis

অনুযায়ী Hannan, Fadil M, Babinsky, Valerie N, Thakker, Rajesh V
প্রকাশিত J Mol Endocrinol (2016)

Association Studies of Calcium-Sensing Receptor (CaSR) Polymorphisms with Serum Concentrations of Glucose and Phosphate, and Vascular Calcification in Renal Transplant Recipients

অনুযায়ী Babinsky, Valerie N., Hannan, Fadil M., Youhanna, Sonia C., Maréchal, Céline, Jadoul, Michel, Devuyst, Olivier, Thakker, Rajesh V.
প্রকাশিত PLoS One (2015)

Calcilytic NPSP795 Increases Plasma Calcium and PTH in an Autosomal Dominant Hypocalcemia Type 1 Mouse Model

অনুযায়ী Hannan, Fadil M, Gorvin, Caroline M, Babinsky, Valerie N, Olesen, Mie K, Stewart, Michelle, Wells, Sara, Cox, Roger D, Nemeth, Edward F, Thakker, Rajesh V
প্রকাশিত JBMR Plus (2020)

Mutations Affecting G-Protein Subunit α(11) in Hypercalcemia and Hypocalcemia

অনুযায়ী Nesbit, M. Andrew, Hannan, Fadil M., Howles, Sarah A., Babinsky, Valerie N., Head, Rosie A., Cranston, Treena, Rust, Nigel, Hobbs, Maurine R., Heath, Hunter, Thakker, Rajesh V.
প্রকাশিত 2013

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

অনুযায়ী Babinsky, Valerie N., Hannan, Fadil M., Gorvin, Caroline M., Howles, Sarah A., Nesbit, M. Andrew, Rust, Nigel, Hanyaloglu, Aylin C., Hu, Jianxin, Spiegel, Allen M., Thakker, Rajesh V.
প্রকাশিত J Biol Chem (2016)

Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations

অনুযায়ী Howles, Sarah A., Hannan, Fadil M., Babinsky, Valerie N., Rogers, Angela, Gorvin, Caroline M., Rust, Nigel, Richardson, Tristan, McKenna, Malachi J., Nesbit, M. Andrew, Thakker, Rajesh V.
প্রকাশিত N Engl J Med (2016)

A calcium-sensing receptor mutation causing hypocalcemia disrupts a transmembrane salt bridge to activate β-arrestin biased signaling

অনুযায়ী Gorvin, Caroline M., Babinsky, Valerie N., Malinauskas, Tomas, Nissen, Peter H., Schou, Anders J., Hanyaloglu, Aylin C., Siebold, Christian, Jones, E. Yvonne, Hannan, Fadil M., Thakker, Rajesh V.
প্রকাশিত Sci Signal (2018)

N-ethyl-N-Nitrosourea (ENU) Induced Mutations within the Klotho Gene Lead to Ectopic Calcification and Reduced Lifespan in Mouse Models

অনুযায়ী Esapa, Christopher T., Hannan, Fadil M., Babinsky, Valerie N., Potter, Paul, Thomas, Gethin P., Croucher, Peter I., Brown, Matthew A., Brown, Steve D. M., Cox, Roger D., Thakker, Rajesh V.
প্রকাশিত PLoS One (2015)

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type...

অনুযায়ী Hannan, Fadil M., Walls, Gerard V., Babinsky, Valerie N., Nesbit, M. Andrew, Kallay, Enikö, Hough, Tertius A., Fraser, William D., Cox, Roger D., Hu, Jianxin, Spiegel, Allen M., Thakker, Rajesh V.
প্রকাশিত Endocrinology (2015)

Gα(11) mutation in mice causes hypocalcemia rectifiable by calcilytic therapy

অনুযায়ী Gorvin, Caroline M., Hannan, Fadil M., Howles, Sarah A., Babinsky, Valerie N., Piret, Sian E., Rogers, Angela, Freidin, Andrew J., Stewart, Michelle, Paudyal, Anju, Hough, Tertius A., Nesbit, M. Andrew, Wells, Sara, Vincent, Tonia L., Brown, Stephen D.M., Cox, Roger D., Thakker, Rajesh V.
প্রকাশিত JCI Insight (2017)

Mutant Mice With Calcium-Sensing Receptor Activation Have Hyperglycemia That Is Rectified by Calcilytic Therapy

অনুযায়ী Babinsky, Valerie N., Hannan, Fadil M., Ramracheya, Reshma D., Zhang, Quan, Nesbit, M. Andrew, Hugill, Alison, Bentley, Liz, Hough, Tertius A., Joynson, Elizabeth, Stewart, Michelle, Aggarwal, Abhishek, Prinz-Wohlgenannt, Maximilian, Gorvin, Caroline M., Kallay, Enikö, Wells, Sara, Cox, Roger D., Richards, Duncan, Rorsman, Patrik, Thakker, Rajesh V.
প্রকাশিত Endocrinology (2017)

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype–phenotype correlations, codon bias and dominant-negative...

অনুযায়ী Hannan, Fadil M., Howles, Sarah A., Rogers, Angela, Cranston, Treena, Gorvin, Caroline M., Babinsky, Valerie N., Reed, Anita A., Thakker, Clare E., Bockenhauer, Detlef, Brown, Rosalind S., Connell, John M., Cook, Jacqueline, Darzy, Ken, Ehtisham, Sarah, Graham, Una, Hulse, Tony, Hunter, Steven J., Izatt, Louise, Kumar, Dhavendra, McKenna, Malachi J., McKnight, John A., Morrison, Patrick J., Mughal, M. Zulf, O'Halloran, Domhnall, Pearce, Simon H., Porteous, Mary E., Rahman, Mushtaqur, Richardson, Tristan, Robinson, Robert, Scheers, Isabelle, Siddique, Haroon, van't Hoff, William G., Wang, Timothy, Whyte, Michael P., Nesbit, M. Andrew, Thakker, Rajesh V.
প্রকাশিত Hum Mol Genet (2015)