Disorders of the calcium-sensing receptor and partner proteins: insights into the molecular basis of calcium homeostasis

Por Hannan, Fadil M, Babinsky, Valerie N, Thakker, Rajesh V
Publicado no J Mol Endocrinol (2016)

Association Studies of Calcium-Sensing Receptor (CaSR) Polymorphisms with Serum Concentrations of Glucose and Phosphate, and Vascular Calcification in Renal Transplant Recipients

Por Babinsky, Valerie N., Hannan, Fadil M., Youhanna, Sonia C., Maréchal, Céline, Jadoul, Michel, Devuyst, Olivier, Thakker, Rajesh V.
Publicado no PLoS One (2015)

Mutations Affecting G-Protein Subunit α(11) in Hypercalcemia and Hypocalcemia

Por Nesbit, M. Andrew, Hannan, Fadil M., Howles, Sarah A., Babinsky, Valerie N., Head, Rosie A., Cranston, Treena, Rust, Nigel, Hobbs, Maurine R., Heath, Hunter, Thakker, Rajesh V.
Publicado em 2013

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Por Babinsky, Valerie N., Hannan, Fadil M., Gorvin, Caroline M., Howles, Sarah A., Nesbit, M. Andrew, Rust, Nigel, Hanyaloglu, Aylin C., Hu, Jianxin, Spiegel, Allen M., Thakker, Rajesh V.
Publicado no J Biol Chem (2016)

Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations

Por Howles, Sarah A., Hannan, Fadil M., Babinsky, Valerie N., Rogers, Angela, Gorvin, Caroline M., Rust, Nigel, Richardson, Tristan, McKenna, Malachi J., Nesbit, M. Andrew, Thakker, Rajesh V.
Publicado no N Engl J Med (2016)

N-ethyl-N-Nitrosourea (ENU) Induced Mutations within the Klotho Gene Lead to Ectopic Calcification and Reduced Lifespan in Mouse Models

Por Esapa, Christopher T., Hannan, Fadil M., Babinsky, Valerie N., Potter, Paul, Thomas, Gethin P., Croucher, Peter I., Brown, Matthew A., Brown, Steve D. M., Cox, Roger D., Thakker, Rajesh V.
Publicado no PLoS One (2015)

The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type...

Por Hannan, Fadil M., Walls, Gerard V., Babinsky, Valerie N., Nesbit, M. Andrew, Kallay, Enikö, Hough, Tertius A., Fraser, William D., Cox, Roger D., Hu, Jianxin, Spiegel, Allen M., Thakker, Rajesh V.
Publicado no Endocrinology (2015)

Gα(11) mutation in mice causes hypocalcemia rectifiable by calcilytic therapy

Por Gorvin, Caroline M., Hannan, Fadil M., Howles, Sarah A., Babinsky, Valerie N., Piret, Sian E., Rogers, Angela, Freidin, Andrew J., Stewart, Michelle, Paudyal, Anju, Hough, Tertius A., Nesbit, M. Andrew, Wells, Sara, Vincent, Tonia L., Brown, Stephen D.M., Cox, Roger D., Thakker, Rajesh V.
Publicado no JCI Insight (2017)

Adaptor protein-2 sigma subunit mutations causing familial hypocalciuric hypercalcaemia type 3 (FHH3) demonstrate genotype–phenotype correlations, codon bias and dominant-negative...

Por Hannan, Fadil M., Howles, Sarah A., Rogers, Angela, Cranston, Treena, Gorvin, Caroline M., Babinsky, Valerie N., Reed, Anita A., Thakker, Clare E., Bockenhauer, Detlef, Brown, Rosalind S., Connell, John M., Cook, Jacqueline, Darzy, Ken, Ehtisham, Sarah, Graham, Una, Hulse, Tony, Hunter, Steven J., Izatt, Louise, Kumar, Dhavendra, McKenna, Malachi J., McKnight, John A., Morrison, Patrick J., Mughal, M. Zulf, O'Halloran, Domhnall, Pearce, Simon H., Porteous, Mary E., Rahman, Mushtaqur, Richardson, Tristan, Robinson, Robert, Scheers, Isabelle, Siddique, Haroon, van't Hoff, William G., Wang, Timothy, Whyte, Michael P., Nesbit, M. Andrew, Thakker, Rajesh V.
Publicado no Hum Mol Genet (2015)