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Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons

Small soluble species of amyloid-beta (Aβ) formed during early peptide aggregation stages are responsible for several neurotoxic mechanisms relevant to the pathology of Alzheimer’s disease (AD), although their interaction with the neuronal membrane is not completely understood. This study quantifies...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ungureanu, Andreea-Alexandra, Benilova, Iryna, Krylychkina, Olga, Braeken, Dries, De Strooper, Bart, Van Haesendonck, Chris, Dotti, Carlos G., Bartic, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865860/
https://ncbi.nlm.nih.gov/pubmed/27173984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25841
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