Amyloid β Oligomers Disrupt Blood–CSF Barrier Integrity by Activating Matrix Metalloproteinases

The blood–CSF barrier (BCSFB) consists of a monolayer of choroid plexus epithelial (CPE) cells that maintain CNS homeostasis by producing CSF and restricting the passage of undesirable molecules and pathogens into the brain. Alzheimer's disease is the most common progressive neurodegenerative d...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Brkic, Marjana, Balusu, Sriram, Van Wonterghem, Elien, Gorlé, Nina, Benilova, Iryna, Kremer, Anna, Van Hove, Inge, Moons, Lieve, De Strooper, Bart, Kanazir, Selma, Libert, Claude, Vandenbroucke, Roosmarijn E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795210/
https://ncbi.nlm.nih.gov/pubmed/26377465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0006-15.2015
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