Amyloid β Oligomers Disrupt Blood–CSF Barrier Integrity by Activating Matrix Metalloproteinases

The blood–CSF barrier (BCSFB) consists of a monolayer of choroid plexus epithelial (CPE) cells that maintain CNS homeostasis by producing CSF and restricting the passage of undesirable molecules and pathogens into the brain. Alzheimer's disease is the most common progressive neurodegenerative d...

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Pubblicato in:J Neurosci
Autori principali: Brkic, Marjana, Balusu, Sriram, Van Wonterghem, Elien, Gorlé, Nina, Benilova, Iryna, Kremer, Anna, Van Hove, Inge, Moons, Lieve, De Strooper, Bart, Kanazir, Selma, Libert, Claude, Vandenbroucke, Roosmarijn E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795210/
https://ncbi.nlm.nih.gov/pubmed/26377465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0006-15.2015
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