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Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons

Small soluble species of amyloid-beta (Aβ) formed during early peptide aggregation stages are responsible for several neurotoxic mechanisms relevant to the pathology of Alzheimer’s disease (AD), although their interaction with the neuronal membrane is not completely understood. This study quantifies...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Ungureanu, Andreea-Alexandra, Benilova, Iryna, Krylychkina, Olga, Braeken, Dries, De Strooper, Bart, Van Haesendonck, Chris, Dotti, Carlos G., Bartic, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865860/
https://ncbi.nlm.nih.gov/pubmed/27173984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25841
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