Label-Free Proteomics Assisted by Affinity Enrichment for Elucidating the Chemical Reactivity of the Liver Mitochondrial Proteome toward Adduction by the Lipid Electrophile 4-hydroxy-2-nonenal (HNE)

The analysis of oxidative stress-induced post-translational modifications remains challenging due to the chemical diversity of these modifications, the possibility of the presence of positional isomers and the low stoichiometry of the modified proteins present in a cell or tissue proteome. Alcoholic...

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Publicado en:Front Chem
Autores principales: Tzeng, Shin-Cheng, Maier, Claudia S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865762/
https://ncbi.nlm.nih.gov/pubmed/27242993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00002
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