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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS Open Bio
Main Authors: Fujii, Yoshifumi, Wakamori, Masatoshi, Umehara, Takashi, Yokoyama, Shigeyuki
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865653/
https://ncbi.nlm.nih.gov/pubmed/27419055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12064
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