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Crystal structure of human nucleosome core particle containing enzymatically introduced CpG methylation

Cytosine methylation, predominantly of the CpG sequence in vertebrates, is one of the major epigenetic modifications crucially involved in the control of gene expression. Due to the difficulty of reconstituting site‐specifically methylated nucleosomal DNA at crystallization quality, most structural...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:FEBS Open Bio
Egile Nagusiak: Fujii, Yoshifumi, Wakamori, Masatoshi, Umehara, Takashi, Yokoyama, Shigeyuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865653/
https://ncbi.nlm.nih.gov/pubmed/27419055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12064
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