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Intra- and inter-nucleosomal interactions of the histone H4 tail revealed with a human nucleosome core particle with genetically-incorporated H4 tetra-acetylation

Post-translational modifications (PTMs) of histones, such as lysine acetylation of the N-terminal tails, play crucial roles in controlling gene expression. Due to the difficulty in reconstituting site-specifically acetylated nucleosomes with crystallization quality, structural analyses of histone ac...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wakamori, Masatoshi, Fujii, Yoshifumi, Suka, Noriyuki, Shirouzu, Mikako, Sakamoto, Kensaku, Umehara, Takashi, Yokoyama, Shigeyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660432/
https://ncbi.nlm.nih.gov/pubmed/26607036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17204
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